Inductively coupled plasma mass spectrometry (ICP-MS) is one of the most important spectroscopic techniques. It is a multi-element technique with extremely high sensitivity and a large linear dynamic range, allowing simultaneous analysis of major components and ultra-trace elements. It is capable of analyzing elements from Li to U and can be applied to both solutions and solids. Solid samples can be analyzed directly (by coupling ICP-MS to a UV laser ablation system) or after dissolution or digestion using a combination of acid, heat and/or pressure.
Typical digestion methods are: microwave digestion (potentially volatile analytes are retained since this is a closed system), Carius digestion (closed system), ashing (oven), hot plate and Peltier.
![Inductively coupled plasma mass spectrometry (ICP-MS) is one of the most important spectroscopic techniques.](https://www.njbing-lab.com/wp-content/uploads/2023/07/plasma.jpg)
Application fields:
Quantitative analysis of trace elements (μg/g in solid; mg/L in liquid) and trace elements (ng/g in solid; ng/L-μg/L in liquid)
in solids, liquids and slurries
Surface, Thin Film and Bulk
Leachables and Extractables
Examples include purity certification, cleaning validation, and contamination identification for a variety of materials and processes of industrial importance to the aerospace, automotive, defense, energy, mining, petroleum, pharmaceutical, and semiconductor industries
Ultrapure water, cooling water, acids, organic solvents, and photolithographic stripping solutions
High-purity oxides and salts, including glasses and high-performance ceramics
High-purity carbon materials, including graphite
Semiconductor material
High-purity metal targets and advanced alloys
organic polymer
Pharmaceuticals, food supplements, biomaterials and medical devices
other materials
In order to reduce the influence of elements on the experimental results, the experimenters will choose high-purity and low-background PFA consumables. The following are common collocations: